Polyhexamethylene biguanide, hydrochloride;
PHMB hydrochloride;
CAS Number: 32289-58-0; 27083-27-8;

El clorhidrato de PHMB, un agente antimicrobiano catiónico de amplio espectro, consigue la esterilización inhibiendo la actividad de la membrana celular.

Como agente antimicrobiano activo de la membrana celular, el PHMB inhibe la actividad bacteriana mejor que la de los hongos, y su mecanismo antimicrobiano es aproximadamente el siguiente:
El PHMB es un compuesto catiónico polimerizado, que es fácilmente adsorbido por varios tipos de bacterias que suelen estar cargadas negativamente, inhibiendo así la función de división de las bacterias y haciendo que éstas pierdan su capacidad reproductiva.

	Solution	Solid
Appearance	Colorless clear to slightly pale yellow liquid	White to slight yellow hygroscopic powder
Odor	Characteristic	Characteristic
Turbidity [NTU]	Max. 10	—
Solid component [％]	19.0 to 21.0	Min. 95.0
Density at 20℃ [g/ml]	1.039 to 1.050	—
pH-Value at 25℃	4 to 6	4 to 7
Absorbance value (1%, 237nm)	Min. 400	Min. 400
Absorbance ratio (237nm / 222nm)	1.2 to 1.6	1.2 to 1.6

The following is the original English text.
El siguiente es el texto original en inglés.

Polyhexamethylene biguanide, hydrochloride;
PHMB hydrochloride

CAS Number: 32289-58-0; 27083-27-8;
Formula:
1. CAS 32289-58-0: (C8H17N5·ClH)n; Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene), hydrochloride;

2. CAS 27083-27-8: (C10H18N8·C6H16N2)x·xClH; Guanidine, N,N»’-1,6-hexanediylbis[N’-cyano-, polymer with1,6-hexanediamine, hydrochloride;

3. CAS: 91403-50-8; EC: 618-745-0;
IUPAC names: Poly(hexamethylenbiguanid)-hydrochlorid

Poly(hexamethylenebiguanide) hydrochloride PHMB, a cationic broad-spectrum antimicrobial agent, achieves bactericidal purpose by inhibiting cell membrane activity.

As a cell membrane active antimicrobial agent, PHMB inhibits bacterial activity better than that of fungi, and its antimicrobial mechanism is roughly as follows:
PHMB is a polymerized cationic compound, which is easily adsorbed by various types of bacteria that are usually negatively charged, thus inhibiting the division function of the bacteria and making the bacteria lose the ability to reproduce.

Features:
1. HPMB has the ability to inhibit Gram-positive bacteria, Gram-negative bacteria, fungi (many kinds of ringworm and mold) and yeast.
2. PHMB has rapid inhibitory effect on E. coli, Staphylococcus aureus and Candida albicans.
3. PHMB: LD50＞5000mg/kg, HPMB is skin friendly, human and environment friendly.

Technical Data:

	20% Solution	Solid
Appearance	Colorless clear to slightly pale yellow liquid	White to slight yellow hygroscopic powder
Odor	Characteristic	Characteristic
Turbidity [NTU]	Max. 10	—
Solid component [％]	19.0 to 21.0	Min. 95.0
Density at 20℃ [g/ml]	1.039 to 1.050	—
pH-Value at 25℃	4 to 6	4 to 7
Absorbance value (1%, 237nm)	Min. 400	Min. 400
Absorbance ratio (237nm / 222nm)	1.2 to 1.6	1.2 to 1.6

Areas of application:
PHMB is widely used in oil field chemicals, water treatment chemicals, daily chemicals, textile printing and dyeing, swimming pool disinfection, flower antiseptic treatment, animal husbandry, aquaculture, agriculture, pet antibacterial, soil improvement, environmental disinfection, disinfection products, etc.
In aquaculture, HPMB can rapidly inhibit Gram-negative bacteria, floating Vibrio, Vibrio parahaemolyticus, Vibrio algolyticus and other harmful bacteria in seawater, and has good preventive and therapeutic effects on various diseases caused by bacteria in South American white shrimp and other aquatic products.

Chemical Name:
Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene),hydrochloride;
Poly(hexamethylenebiguanide) hydrochloride;
Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl), hydrochloride;
Poly(hexamethylene diguanide) hydrochloride；
Poly[imino(carbonimidoyl)imino(carbonimidoyl)iminohexane-1,6-diyl] hydrochloride (1:?);
Guanidine,N,N»’-1,6-hexanediylbis[N’-cyano-,polymer with 1,6-hexanediamine, hydrochloride;
N,N»’-1,6-Hexanediylbis(N’-cyanoguanidine),hexamethylenediamine polymer, hydrochloride;