{"id":3460,"date":"2023-09-02T12:27:40","date_gmt":"2023-09-02T04:27:40","guid":{"rendered":"https:\/\/www.green-mountainchem.com\/?p=3460"},"modified":"2025-10-22T15:57:35","modified_gmt":"2025-10-22T07:57:35","slug":"phmb","status":"publish","type":"post","link":"https:\/\/www.green-mountainchem.com\/pt\/phmb\/","title":{"rendered":"PHMB"},"content":{"rendered":"\n

Polyhexamethylene biguanide, hydrochloride;
<\/strong>PHMB hydrochloride;
CAS Number: 32289-58-0; 27083-27-8;<\/p>\n\n\n\n

\n
PHMG<\/strong><\/a><\/div>\n\n\n\n
PHMB<\/strong><\/a><\/div>\n\n\n\n
Bronopol<\/strong><\/a><\/div>\n\n\n\n
CMIT\/MIT<\/strong><\/a><\/div>\n\n\n\n
DBNPA<\/strong><\/a><\/div>\n<\/div>\n\n\n\n

O cloridrato de PHMB, um agente antimicrobiano cati\u00f4nico de amplo espectro, atinge o objetivo bactericida inibindo a atividade da membrana celular.<\/p>\n\n\n\n

Como um agente antimicrobiano ativo na membrana celular, o PHMB inibe a atividade bacteriana melhor do que a dos fungos, e seu mecanismo antimicrobiano \u00e9 mais ou menos o seguinte:
O PHMB \u00e9 um composto cati\u00f4nico polimerizado, que \u00e9 facilmente adsorvido por v\u00e1rios tipos de bact\u00e9rias que geralmente t\u00eam carga negativa, inibindo assim a fun\u00e7\u00e3o de divis\u00e3o das bact\u00e9rias e fazendo com que elas percam sua capacidade reprodutiva.<\/p>\n\n\n\n

<\/td>PHMB 20% Solution<\/td>PHMB Solid<\/td><\/tr>
Appearance<\/td>Colorless clear to slightly pale yellow liquid<\/td>White to slight yellow hygroscopic powder<\/td><\/tr>
Odor<\/td>Characteristic<\/td>Characteristic<\/td><\/tr>
Turbidity [NTU]<\/td>Max. 10<\/td>—<\/td><\/tr>
Solid component [\uff05]<\/td>19.0 to 21.0<\/td>Min. 95.0<\/td><\/tr>
Density at <\/a>20\u2103 [g\/ml]<\/td>1.039 to 1.050<\/td>—<\/td><\/tr>
pH-Value at 25\u2103<\/td>4 to 6<\/td>4 to 7<\/td><\/tr>
Absorbance value (1%, 237nm)<\/td>Min. 400<\/td>Min. 400<\/td><\/tr>
Absorbance ratio (237nm \/ 222nm)<\/td>1.2 to 1.6<\/td>1.2 to 1.6<\/td><\/tr><\/tbody><\/table>
PHMB, CAS 27083-27-8, 32289-58-0<\/em><\/figcaption><\/figure>\n\n\n\n

The following is the original English text.
A seguir, o texto original em ingl\u00eas.<\/p>\n\n\n\n

Polyhexamethylene biguanide, hydrochloride;
<\/strong>PHMB hydrochloride<\/p>\n\n\n\n

CAS Number: 32289-58-0; 27083-27-8;
Formula:
1. CAS 32289-58-0: (C8H17N5\u00b7ClH)n; Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene), hydrochloride;

2. CAS 27083-27-8: (C10H18N8\u00b7C6H16N2)x\u00b7xClH; Guanidine, N,N”’-1,6-hexanediylbis[N’-cyano-, polymer with1,6-hexanediamine, hydrochloride;<\/p>\n\n\n\n

3. CAS: 91403-50-8; EC: 618-745-0;
IUPAC names: Poly(hexamethylenbiguanid)-hydrochlorid<\/p>\n\n\n\n

Related chemical:
PHMB; CAS# 28757-47-3;
(C8H17N5)n
Poli (iminocarbonimidoiliminocarbonimidoilimino-1 ,6-hexanodiil);
Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl); Polyhexamethylenebiguanidine; PHMB without HCl;<\/p>\n\n\n\n

PHMB hydrochloride, a cationic broad-spectrum antimicrobial agent, achieves bactericidal purpose by inhibiting cell membrane activity.<\/p>\n\n\n\n

As a cell membrane active antimicrobial agent, PHMB inhibits bacterial activity better than that of fungi, and its antimicrobial mechanism is roughly as follows:
PHMB is a polymerized cationic compound, which is easily adsorbed by various types of bacteria that are usually negatively charged, thus inhibiting the division function of the bacteria and making the bacteria lose the ability to reproduce.<\/p>\n\n\n\n

Features:
<\/strong>1. HPMB has the ability to inhibit Gram-positive bacteria, Gram-negative bacteria, fungi (many kinds of ringworm and mold) and yeast.
2. PHMB has rapid inhibitory effect on E. coli, Staphylococcus aureus and Candida albicans.
3. PHMB: LD50\uff1e5000mg\/kg, HPMB is skin friendly, human and environment friendly.<\/p>\n\n\n\n

<\/p>\n\n\n\n

Abbreviation<\/strong><\/td>Product Name<\/strong><\/td>CAS No.<\/strong><\/td>Appearance<\/strong><\/td>Uses<\/strong><\/td><\/tr>
Benzalkonium chloride<\/a><\/td>Quaternary ammonium compounds,benzyl-C12-14-alkyldimethyl, chlorides<\/a><\/td>85409-22-9<\/td>White Powder; Liquid<\/strong><\/td>Powder is used in cosmetics, etc.<\/td><\/tr>
Benzyl Dodecyl Dimethyl
Ammonium Bromide<\/td>		Benzenemethanaminium, N-dodecyl-N,N-dimethyl-, bromide<\/td>7281-04-1<\/td>20% to 95%, Liquid to Paste<\/td><\/td><\/tr>
DDAC<\/a><\/td>Didecyldimethylammonium Chloride<\/a><\/td>7173-51-5<\/td>40%, 80% Liquid<\/td>Medical hygiene, wet wipes, cosmetics, etc.<\/td><\/tr>
CPC<\/a><\/td>Cetylpyridnium Chloride<\/a><\/td>123-03-5<\/td>White powder<\/td>Oral care,
wet wipes, cosmetics, etc.<\/td><\/tr>
Benzethonium chloride<\/td>Benzethonium chloride<\/td>121-54-0<\/td>White powder<\/td>Wipes, lotion, etc.<\/td><\/tr>
C12 Benzyl
Ammonium Bromide<\/td>		Benzyl Dodecyl Dimethyl
Ammonium Bromide<\/td>		7281-04-1<\/td>White powder<\/td><\/td><\/tr>
Parabens<\/td>Methyl\/ Ethyl\/ Propyl\/ Butyl paraben<\/td>—<\/td>White crystalline powder<\/strong><\/td>Cosmetics, etc.<\/td><\/tr>
DBNPA<\/a><\/td>Acetamide,2,2-dibromo-2-cyano-<\/a><\/td>10222-01-2<\/td>White crystalline powder; Liquid<\/strong><\/td>Algaecide in cooling water circulation system, etc.<\/td><\/tr>
Bronopol<\/a><\/td>2-Bromo-2-nitro-1,3-propanediol<\/a><\/td>52-51-7<\/td>White crystalline powder<\/strong><\/td>Water treatment bactericide and algaecide, cosmetics, etc.<\/td><\/tr>
CMIT\/MIT<\/a><\/td>3(2H)-Isothiazolone,5-chloro-2-methyl-,mixt. with 2-methyl-3(2H)-isothiazolone<\/a><\/td>55965-84-9<\/td>Liquid<\/strong><\/td>Water treatment anti-slime and algaecide, etc.<\/td><\/tr>
PHMB<\/a><\/td>Poly(hexamethylenebiguanide) hydrochloride<\/a><\/td>32289-58-0;
27083-27-8;<\/td>		Liquid<\/strong><\/td><\/td><\/tr>
PHMG<\/a><\/td>Polyhexamethyleneguanidine hydrochloride; PHMG chloride<\/a><\/td>57028-96-3<\/td>Liquid<\/strong><\/strong><\/td>Water treatment, swimming pool, etc.<\/td><\/tr>
CHD-G<\/td>Chlorhexidine digluconate<\/td>18472-51-0<\/td>Liquid<\/td><\/td><\/tr>
CHD-A<\/td>Chlorhexidine di(acetate)<\/td>56-95-1<\/td>Liquid<\/td><\/td><\/tr>
<\/td>Zinc Castor Oleate<\/td>13040-19-2<\/td>Liquid<\/td>Odor scavenger<\/td><\/tr><\/tbody><\/table>
List of Biocidal active substances<\/em><\/figcaption><\/figure>\n\n\n\n

Areas of application<\/strong>:
PHMB is widely used in oil field chemicals, water treatment chemicals, daily chemicals, textile printing and dyeing, swimming pool disinfection, flower antiseptic treatment, animal husbandry, aquaculture, agriculture, pet antibacterial, soil improvement, environmental disinfection, disinfection products, etc.
In aquaculture, HPMB can rapidly inhibit Gram-negative bacteria, floating Vibrio, Vibrio parahaemolyticus, Vibrio algolyticus and other harmful bacteria in seawater, and has good preventive and therapeutic effects on various diseases caused by bacteria in South American white shrimp and other aquatic products.<\/p>\n\n\n\n


Chemical Name:
<\/strong>Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene),hydrochloride;
Poly(hexamethylenebiguanide) hydrochloride;
Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl), hydrochloride;
Poly(hexamethylene diguanide) hydrochloride\uff1b
Poly[imino(carbonimidoyl)imino(carbonimidoyl)iminohexane-1,6-diyl] hydrochloride (1:?);
Guanidine,N,N”’-1,6-hexanediylbis[N’-cyano-,polymer with 1,6-hexanediamine, hydrochloride;
N,N”’-1,6-Hexanediylbis(N’-cyanoguanidine),hexamethylenediamine polymer, hydrochloride;<\/p>\n","protected":false},"excerpt":{"rendered":"

CAS Number: 32289-58-0; 27083-27-8;
\nPolyhexamethylene biguanide, hydrochloride;
\nPHMB hydrochloride;
\nPHMB is raw materials for the production of biocide, bactericide, disinfectant, water treatment chemicals.<\/p>\n

PHMB is widely used in oil field chemicals, water treatment chemicals, daily chemicals, textile printing and dyeing, swimming pool disinfection, flower antiseptic treatment, animal husbandry, aquaculture, agriculture, pet antibacterial, soil improvement, environmental disinfection, disinfection products, etc.<\/p>\n","protected":false},"author":1,"featured_media":4657,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_locale":"pt_BR","_original_post":"https:\/\/www.green-mountainchem.com\/?p=2092","footnotes":""},"categories":[445,10],"tags":[95,93,430,84],"class_list":["post-3460","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biocidal-active-substances","category-water-treatment","tag-bactericide","tag-biocide","tag-phmb","tag-water-treatment-chemicals","pt-BR"],"_links":{"self":[{"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/posts\/3460","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/comments?post=3460"}],"version-history":[{"count":0,"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/posts\/3460\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/media\/4657"}],"wp:attachment":[{"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/media?parent=3460"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/categories?post=3460"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.green-mountainchem.com\/wp-json\/wp\/v2\/tags?post=3460"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}